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Volume 357:945-946 August 30, 2007 Number 9
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Long-Term Follow-up after Treatment of Rabies by Induction of Coma

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To the Editor: In 2005, Willoughby and colleagues1 reported on a 15-year-old girl's survival from rabies encephalitis — the sixth such case that had been reported in humans — after treatment with a novel therapeutic regimen that included ketamine, ribavirin, and amantadine. Five months after exposure, she still had dysarthria, weakness in the left hand and foot, bilateral extensor plantar response, generalized choreoathetosis, intermittent dystonia, and a lurching gait. Here we report on the functional outcomes 18 months and 27 months after her initial exposure to a rabid bat.

Her generalized choreoathetosis completely resolved by 2006. A trial of therapy . . . [Full Text of this Article]


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