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Correspondence
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Volume 358:1078-1079 March 6, 2008 Number 10
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Graves' Disease, Thymus Enlargement, and Hypercalcemia

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To the Editor: A previously healthy 32-year-old man presented with dyspnea on exertion. Chest radiography showed mediastinal enlargement without pulmonary abnormalities. Magnetic resonance imaging (MRI) showed a mass in the anterior mediastinum with homogeneous gadolinium-diethylenetriamine pentaacetic acid enhancement. An increase in the total serum calcium level (2.98 mmol per liter [normal range, 2.10 to 2.65]) and suppression of thyrotropin (<0.01 mU per liter [normal range, 0.40 to 4.00]) were found.

The patient was referred to our thyroid unit. Increased levels of free thyroid hormones (triiodothyronine and thyroxine), anti–thyrotropin-receptor antibody (6.9 U per liter [normal value, <1.5]), and ionized calcium (1.34 . . . [Full Text of this Article]



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