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Volume 358:1089-1092 March 13, 2008 Number 11 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Africa is facing the worst tuberculosis epidemic since the advent of the antibiotic era. Driven by a generalized human immunodeficiency virus (HIV) epidemic and compounded by weak health care systems, inadequate laboratories, and conditions that promote transmission of infection, this devastating situation has steadily worsened, exacerbated by the emergence of drug-resistant strains of tuberculosis.

Africa, home to 11% of the world's population, carries 29% of the global burden of tuberculosis cases and 34% of related deaths, and the challenges of controlling the disease in the region have never been greater. The World Health Organization (WHO) estimates that the average incidence . . . [Full Text of this Article]

Source Information

Dr. Chaisson is the director of the Center for Tuberculosis Research at the Johns Hopkins University School of Medicine, Baltimore. Dr. Martinson is the deputy director of the Perinatal HIV Research Unit, University of the Witwatersrand, Soweto, South Africa.

A slide presentation on tuberculosis and HIV in Africa may be seen at www.nejm.org.

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