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Volume 358:1195-1197 March 13, 2008 Number 11
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Cetuximab for Colorectal Cancer

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 by Jonker, D. J.
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To the Editor: The study by Jonker et al. (Nov. 15 issue)1 showed that cetuximab improved survival among patients with colorectal cancer, but the authors give no details regarding sites of metastases in the cetuximab group. Were metastatic sites in patients receiving cetuximab correlated with survival? The authors do not mention thromboembolism, which may be associated with poor survival among patients with cancer.2 Was cetuximab associated with an increased risk of thromboembolism?


Feng Yang, M.D.
Deliang Fu, M.D.
Quanxing Ni, M.D.
Huashan Hospital
Shanghai 200040, China
surgeonfu@yahoo.com.cn

  1. Jonker DJ, O'Callaghan CJ, Karapetis CS, et al. Cetuximab for the treatment of colorectal cancer. N Engl J Med 2007;357:2040-2048. [Free Full Text]
  2. Mandalà M, Moro C, Labianca R, Ferretti G. Erlotinib in pancreatic cancer patients: do we need more information from the NCIC CTG trial? J Clin Oncol 2007;25:4320-4321. [Free Full Text]

 
To the Editor: It would be useful to know whether Jonker et al. . . . [Full Text of this Article]




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