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Volume 358:1324-1325 March 27, 2008 Number 13
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In Search of New Ideas for Global Health
Tadataka Yamada, M.D.

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The recent failure of another potential vaccine against human immunodeficiency virus (HIV) underscores the enormous challenges of tackling diseases whose heaviest burden falls on the developing world. A quarter of a century after the first report of AIDS, our knowledge about how an HIV vaccine might work is still distressingly limited. It seems clear that neither current dogma nor traditional thinking is likely to get us to the next step. Truly creative ideas will be required.

I must confess to having learned the hard way that embracing new thinking, as difficult as it may be, is crucial for the advancement . . . [Full Text of this Article]


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Dr. Yamada is president of the Global Health Program of the Bill and Melinda Gates Foundation, Seattle.



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