The recent failure of another potential vaccine against humanimmunodeficiency virus (HIV) underscores the enormous challengesof tackling diseases whose heaviest burden falls on the developingworld. A quarter of a century after the first report of AIDS,our knowledge about how an HIV vaccine might work is still distressinglylimited. It seems clear that neither current dogma nor traditionalthinking is likely to get us to the next step. Truly creativeideas will be required.
I must confess to having learned the hard way that embracingnew thinking, as difficult as it may be, is crucial for theadvancement . . . [Full Text of this Article]
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Dr. Yamada is president of the Global Health Program of the Bill and Melinda Gates Foundation, Seattle.
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