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Previous Volume 358:1394-1396 March 27, 2008 Number 13 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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The thoughtful clinician takes it to be self-evident that intensity of therapy should be proportional to risk of disease.^1,2 Ever since Bigger coined the term "risk stratification" to characterize this intuitive process,³ more than 3000 articles (according to a recent PubMed literature search) have been published on the subject — at a rate that is doubling every 5 years.⁴ Nearly 40% of these articles focus on cardiovascular medicine, where "risk stratification" has become something of a mantra for rational, evidence-based clinical management.

Predicting who will have a cardiovascular event is indeed an important clinical and societal goal. Currently, the United . . . [Full Text of this Article]

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From the Christiana Care Health System, Newark, DE (W.S.W.); and Cedars–Sinai Medical Center, Los Angeles (G.A.D.).

Related Letters:

Coronary Calcium and Events in Four Ethnic Groups
Payne P. W. Jr., Littmann L., Burtey S., Dussol B., Brunet P., Goyal S. K., Punnam S. R., Nasir K., Budoff M. J., Blumenthal R., Guerci A. D., Bild D. E., Kronmal R. A., Weintraub W. S., Diamond G. A.
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N Engl J Med 2008; 359:202-204, Jul 10, 2008. Correspondence

This article has been cited by other articles:

• Payne, P. W. Jr., Littmann, L., Burtey, S., Dussol, B., Brunet, P., Goyal, S. K., Punnam, S. R., Nasir, K., Budoff, M. J., Blumenthal, R., Guerci, A. D., Bild, D. E., Kronmal, R. A., Weintraub, W. S., Diamond, G. A. (2008). Coronary Calcium and Events in Four Ethnic Groups. NEJM 359: 202-204 [Full Text]