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A 60-year-old man infected with the human immunodeficiency virus (HIV) (CD4 count of 450 per cubic millimeter and HIV viral load of <50 copies per milliliter) who had HIV-associated dementia was admitted to our hospital because of an altered mental status, a temperature of 101°F (38.3°C), and seizure-like activity. His medications included efavirenz, emtricitabine, tenofovir, and pravastatin sodium. Empirical treatment with intravenous acyclovir (10 mg per kilogram of body weight) and antibiotics was initiated before the patient underwent a lumbar puncture. Two hours after the administration of acyclovir, his urine became cloudy and white in the proximal portion of the . . . [Full Text of this Article] |
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