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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the author's clinical recommendations.
A 65-year-old asymptomatic man is concerned about his risk of osteoporosis. His mother died after a hip fracture at 74 years of age. The patient has no history of fractures but has lost 7.6 cm (3 in.) in height; he does not smoke and has never taken corticosteroids. He drinks two glasses of beer (16 oz, or about 0.5 liter, each) per
The Clinical Problem
Secondary Causes of Bone Loss in Men
Natural History of Bone Loss in Men
Strategies and Evidence
Diagnosis
Additional Testing
Laboratory Tests
Vertebral-Fracture Assessment
Management
Nonpharmacologic Therapy
Pharmacologic Therapy
Bisphosphonates
Anabolic Agents
Testosterone Therapy
Areas of Uncertainty
Guidelines
Conclusions and Recommendations
Source Information
From the Department of Medicine, Royal Melbourne Hospital/Western Hospital, and the Department of Endocrinology, University of Melbourne, Western Hospital, Melbourne, Victoria, Australia.
An audio version of this article is available at www.nejm.org.
Address reprint requests to Dr. Ebeling at the Department of Medicine (RMH/WH), Western Hospital, Gordon St., Footscray 3011, Victoria, Australia, or at peterre@unimelb.edu.au.
Related Letters:
Osteoporosis in Men
Ott S. M., Lems W. F., Geusens P. P.M.M., Joy M., Ebeling P. R.
Extract |
Full Text |
PDF
N Engl J Med 2008;
359:868-869, Aug 21, 2008.
Correspondence
This article has been cited by other articles:
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