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Correspondence
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Volume 358:1518-1521 April 3, 2008 Number 14
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Patent Foramen Ovale and Cryptogenic Stroke

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 by Handke, M.
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To the Editor: It is hard to accept that a study of patent foramen ovale and cryptogenic stroke, reported by Handke et al. (Nov. 29, 2007, issue),1 would show that almost half of 596 consecutive patients admitted to a major university medical center for acute brain ischemia had a cryptogenic stroke, especially since 272 cases of stroke had no angiographic studies done (neither magnetic resonance nor digital-subtraction angiography). Without these critically important imaging studies, how can such a large group of cases of stroke be declared cryptogenic?

Table 1 of the article contains data on 276 stroke cases of known . . . [Full Text of this Article]




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