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A 1-day-old female infant was admitted to the neonatal intensive care unit of this hospital because of intermittent apnea and cyanosis. The day before admission, the patient was born at another hospital at 41 weeks 4 days' gestation to a 33-year-old primigravid mother. After 44 hours of labor, during which the amniotic membranes were artificially ruptured (17 hours before delivery) and the mother's temperature rose to 38.0°C, with a white-cell count of 26,700 per cubic millimeter, a cesarean section was performed because of failure of labor to progress. The infant weighed 4176 g (90th percentile) at birth, and the Apgar
Differential Diagnosis
Chorioamnionitis
Apneic Spells
Neonatal Seizures
Perinatal Ischemic Stroke
Fetal Thrombophilia
Neonatal Infection
Severe Placental–Fetal Vascular Lesions
Clinical Diagnosis
Dr. Raymond W. Redline's Diagnosis
Pathological Discussion
Discussion of Management
Anatomical Diagnosis
Source Information
From the Department of Pathology, University Hospitals Case Medical Center, Cleveland (R.W.R.); the Departments of Radiology (P.S.), Pediatric Cardiology (M.E.K.), Pediatric Neurology (K.S.K.), Pediatric Hematology/Oncology (E.F.G.), and Pathology (D.J.R.), Massachusetts General Hospital, Boston; the Department of Pathology , Case Western Reserve University School of Medicine, Cleveland (R.W.R.); and the Departments of Radiology (P.S.), Pediatrics (M.E.K., K.S.K., E.F.G.), and Pathology (D.J.R.), Harvard Medical School, Boston.
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