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Previous Volume 358:1763-1764 April 17, 2008 Number 16 Next

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By Paul Korner. 690 pp., illustrated. New York, Oxford University Press, 2007. $98.50. ISBN 978-0-19-509483-1.

Many people believe that the cause of essential hypertension remains unknown. In Essential Hypertension and Its Causes, Paul Korner aims to identify the pathogenesis of essential hypertension by bringing together a considerable amount of knowledge in a coherent and clinically relevant manner. He makes a strong argument that instead of originating from the kidneys, essential hypertension is triggered primarily through the nervous system and is later reinforced by nonneural factors.

The book has three interwoven objectives: to define the main initiating causes of essential hypertension, to elucidate the mechanisms by which blood pressure is raised, and to assess the . . . [Full Text of this Article]

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