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Correction to Triggs and Cros, N Engl J Med 357(26):2707-2715 December 27, 2007.

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Volume 358:1869-1870 April 24, 2008 Number 17
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Case 40-2007: A Man with Weakness in the Hands

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by Triggs, W. J.
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To the Editor: In the Case Record involving a 38-year-old man with multifocal motor neuropathy, discussed by Triggs and Cros (Dec. 27 issue),1 Triggs emphasizes that it is important to distinguish multifocal motor neuropathy from amyotrophic lateral sclerosis or other motor neuron diseases because it responds favorably to immunotherapy. He mentions that plasma exchange, cyclophosphamide, and intravenous immune globulin are all beneficial. However, only treatment with intravenous immune globulins has been shown to be beneficial in randomized, controlled trials.2 Cyclophosphamide has been reported to be effective but only anecdotally, and its toxicity precludes long-term use, which is usually necessary in . . . [Full Text of this Article]



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