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Previous Volume 358:1963-1964 May 1, 2008 Number 18 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Bissler et al. and Davies et al. (Jan. 10 issue)^1,2 report the beneficial effects of sirolimus on renal angiolipoma in patients with lymphangioleiomyomatosis (LAM). In contrast to the findings of Bissler et al., Davies et al. observed no benefit in lung function from sirolimus in their patients with LAM. We now describe a 41-year-old woman with LAM who underwent right-lung transplantation and subsequently had radiologic improvement in the native lung after undergoing sirolimus therapy, which was used in combination with cyclosporine and prednisolone for post-transplantation immunosuppression.

Histologic examination of the explanted lung confirmed the diagnosis of LAM. . . . [Full Text of this Article]

Related Letters:

Sirolimus Therapy in Tuberous Sclerosis or Sporadic Lymphangioleiomyomatosis
Davies D. M., Johnson S. R., Tattersfield A. E., Kingswood J. C., Cox J. A., McCartney D. L., Doyle T., Elmslie F., Saggar A., de Vries P. J., Sampson J. R.
Extract | Full Text | PDF  
N Engl J Med 2008; 358:200-203, Jan 10, 2008. Correspondence

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