FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 358:2077-2078 May 8, 2008 Number 19 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear PubMed Citation

To the Editor: The long-QT syndrome and catecholaminergic polymorphic ventricular tachycardia are the most common inherited cardiac channelopathies.¹ Although the disease mechanisms for these two disorders differ, the resulting arrhythmias are similar, and both are triggered by sympathetic stimulation.^2,3 We identified the coexistence of the two diseases in one family.

A family with a history of recurrent sudden death was studied. During the past 30 years, nine members have died suddenly between 7 and 40 years of age. A borderline QT interval corrected for heart rate (QTc) of 450 msec in one asymptomatic relative (identified as V-1 in Figure 1. . . [Full Text of this Article]

This article has been cited by other articles:

• Medeiros-Domingo, A., Bhuiyan, Z. A., Tester, D. J., Hofman, N., Bikker, H., van Tintelen, J. P., Mannens, M. M.A.M., Wilde, A. A.M., Ackerman, M. J. (2009). The RYR2-Encoded Ryanodine Receptor/Calcium Release Channel in Patients Diagnosed Previously With Either Catecholaminergic Polymorphic Ventricular Tachycardia or Genotype Negative, Exercise-Induced Long QT Syndrome A Comprehensive Open Reading Frame Mutational Analysis.. J Am Coll Cardiol 54: 2065-2074 [Abstract] [Full Text]