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Volume 358:193-195 January 10, 2008 Number 2
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Long-Term Follow-up of the West of Scotland Coronary Prevention Study

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by Ford, I.
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To the Editor: Ford et al. (Oct. 11 issue)1 report long-term follow-up data from the West of Scotland Coronary Prevention Study (WOSCOPS), which showed that statin treatment for 5 years provided an ongoing reduction in cardiovascular events for an additional 10 years. Stabilization of existing plaque, slowing of the progression of coronary artery disease, and possibly regression of atherosclerosis are suggested as potential mechanisms for this benefit.

This follow-up study adjusted for the presence or absence of a history of diabetes at entry. Previous data from WOSCOPS have shown that randomized assignment to pravastatin therapy resulted in a 30% reduction . . . [Full Text of this Article]



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