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Volume 358:2184-2185 May 15, 2008 Number 20
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Letting the Genome Out of the Bottle

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 by Hunter, D. J.
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To the Editor: The Perspective article by Hunter et al. (Jan. 10 issue)1 concludes that commercialization of personal genomics is premature in light of the lack of data to support the analytic and clinical validity and clinical utility of these tests. Although the authors' description of the current state of the art is accurate, they and others2 minimize the important point that clinical practice has already been influenced by the possibility of personal genomics, and it is consumers' attitudes — not outcomes data — that are the critical drivers of such changes.

Despite what most geneticists and physicians would view . . . [Full Text of this Article]




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