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Correspondence
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Volume 358:2296-2298 May 22, 2008 Number 21
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Athletes with Repolarization Abnormalities

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 by Pelliccia, A.
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To the Editor: Pelliccia et al. (Jan. 10 issue)1 report long-term follow-up data on 81 athletes with deeply inverted T waves on electrocardiograms (ECGs), who had no apparent cardiac disease, selected from a cohort of 12,550 trained athletes. Among these 81 athletes, 5 (6%) ultimately proved to have cardiomyopathies, and 3 of the 5 had hypertrophic cardiomyopathy. We would like to reconsider the relation between deeply inverted T waves and hypertrophic cardiomyopathy in apparently healthy young persons, whether or not they are athletes. In our opinion, myocardial hypertrophy does not represent the true hypertrophic cardiomyopathy phenotype. Geisterfer-Lowrance et al.2 have . . . [Full Text of this Article]




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