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Volume 358:2316-2317 May 29, 2008 Number 22
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Exploiting a Research Underclass in Phase 1 Clinical Trials
Carl Elliott, M.D., Ph.D., and Roberto Abadie, Ph.D.

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In November 1996, the Wall Street Journal reported that Eli Lilly was paying homeless alcoholics from a local shelter to participate in safety testing of new drugs at its trial site in Indianapolis.1 "These individuals want to help society," asserted Lilly's director of clinical pharmacology. The subjects, however, said they took part for easy money and free room and board. Although Lilly reportedly offered the lowest per diem in the business, it managed to attract poor subjects from all over the country.1 The medical director of the local Homeless Initiative Program said Lilly had created a "shadow economy" of paid . . . [Full Text of this Article]


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Dr. Elliott is a professor at the Center for Bioethics at the University of Minnesota, Twin Cities. Dr. Abadie is an anthropologist and independent scholar who recently completed a research fellowship in the Bioethics Research Program, Mayo Clinic, Rochester, MN.



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