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Book Review
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Volume 358:2416 May 29, 2008 Number 22
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Tumor Angiogenesis: Basic Mechanisms and Cancer Therapy

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Edited by Dieter Marmé and Norbert Fusenig. 845 pp., illustrated. Berlin, Springer, 2008. $369. ISBN 978-3-540-33176-6.

In January, the world lost a visionary in cancer research, M. Judah Folkman. Folkman, who died while traveling to a Keystone symposium to give the keynote address, proposed nearly four decades ago that attacking the tumor vasculature could improve outcomes for patients with cancer in its advanced stages. These insights provided the foundation for the development of antiangiogenic therapies and changed the standard of care for patients with specific cancers (as well as for patients with ocular macular degeneration). It is fitting that this book, Tumor Angiogenesis, begins with a chapter written by Folkman in which he comprehensively reviews the . . . [Full Text of this Article]




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