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Previous Volume 358:2521-2522 June 5, 2008 Number 23 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Kamar and colleagues (Feb. 21 issue)¹ report eight cases of chronic hepatitis E virus (HEV) infection in immunosuppressed organ-transplant recipients, a constellation that was hitherto not observed. One wonders whether the persistence of HEV infection is a more general consequence of immunosuppression, which has implications for all so-called nonpersistent pathogens. Previously, we observed prolonged and possibly chronic shedding of human metapneumovirus in two patients with cancer who were immunosuppressed because they were receiving chemotherapy.² Furthermore, it was recently reported that immunosuppression induced by lactate dehydrogenase–elevating virus led to increases in the severity and duration of the acute . . . [Full Text of this Article]

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