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Volume 358:2526-2527 June 5, 2008 Number 23
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Do No Harm: How a Magic Bullet for Prostate Cancer Became a Medical Quandary

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By Stewart Justman. 236 pp. Chicago, Ivan R. Dee, 2008. $26. ISBN 978-1-56663-627-8.

In 2003, the Journal published an article on the influence of finasteride in the prevention of prostate cancer. This study demonstrated that men who took the drug experienced a 24.8% lower risk of prostate cancer, as compared with men who received a placebo, but had a higher risk of high-grade disease. This startling finding raised an ethical dilemma about the risk–benefit ratio and the question of whether any risk was too high. Stewart Justman is well credentialed to attack this thorny question. He is a noted author, a professor of liberal studies at the University of Montana, a lay member . . . [Full Text of this Article]




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