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An otherwise healthy 36-year-old man presented with a 6-day history of bleeding gums and abdominal pain in the left upper quadrant. He reported having had fevers, fatigue, decreased appetite, and unintentional weight loss of 10 lb (4.5 kg) during the previous month. On physical examination, red, swollen gingivae (Panel A), tender submandibular lymph nodes, and a palpable spleen were noted. Laboratory evaluation revealed a peripheral-blood white-cell count of 194,100 per cubic millimeter, with 44% blasts, and a peripheral-blood platelet count of 12,000 per cubic millimeter. Examination of a bone marrow–biopsy specimen showed acute myelomonocytic leukemia with dysplastic eosinophils with a . . . [Full Text of this Article] |
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