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A 33-year-old pregnant woman was admitted to the hospital at 30.7 weeks' gestation because of swelling of the left breast, shortness of breath, and tachycardia.
The patient had received prenatal care at this hospital since 9.7 weeks' gestation. The blood type was O Rh-positive and the woman was immune to rubella. Test results for hepatitis B surface antigen, chlamydia and gonorrhea infection, rapid plasma reagin, cystic fibrosis–carrier status, and fetal aneuploidy were negative, and quadruple-marker screening confirmed low risks for fetal aneuploidy and neural-tube defects. At 18.6 weeks' gestation, ultrasonographic examination revealed normal fetal anatomy and growth. Other laboratory-test results
Differential Diagnosis
Breast Enlargement in Pregnancy
Mastitis
Breast Cancer
Venous Obstruction
Differential Diagnosis of a Mediastinal Mass
Lymphomas Involving the Mediastinum
Lymphomas Involving the Breast
Lymphomas in Pregnancy
Management of Lymphomas in Pregnancy
Treatment for This Patient
Clinical Diagnosis
Dr. Lawrence N. Shulman's Diagnosis
Pathological Discussion
Anatomical Diagnosis
Source Information
From the Department of Medical Oncology, Dana–Farber Cancer Institute (L.N.S.); the Department of Medicine, Brigham and Women's Hospital (L.N.S.); the Departments of Radiology (R.A.H.) and Pathology (J.A.F.), Massachusetts General Hospital; and the Departments of Medicine (L.N.S.), Radiology (R.A.H.), and Pathology (J.A.F.), Harvard Medical School — all in Boston.
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