The ultimate goal of personalized medicine is to comprehensivelyidentify genetic differences among persons and to correlatespecific genetic features (or combinations of genetic features)with the differential risk of human diseases or the efficacyof certain therapeutic interventions. This goal is likely tobe achieved when we are able to identify all relevant formsof genetic variation in each person and are able to interpretthis information in a clinically meaningful manner.
The Human Genome Project revealed a very high degree of similaritybetween the DNA sequences of any two persons. These similaritiesunite us as a species. On . . . [Full Text of this Article]
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From the Department of Pathology (C.L., C.C.M.) and the Department of Obstetrics, Gynecology, and Reproductive Biology (C.C.M.), Brigham and Women's Hospital, Harvard Medical School, Boston.
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