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Correspondence
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Volume 358:859-860 February 21, 2008 Number 8
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Chronic Hepatitis E with Cirrhosis in a Kidney-Transplant Recipient

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To the Editor: Hepatitis E virus (HEV) is an important cause of acute viral hepatitis worldwide.1 Kamar et al. in this issue of the Journal2 and others3,4 have recently suggested that HEV infection might result in chronic hepatitis in immunocompromised patients. We report a rapidly progressing case of cirrhosis in a renal-transplant recipient with chronic HEV infection.

A 52-year-old man who had undergone kidney transplantation in March 2005 presented with increased aminotransferase levels in June 2006. Four months later, the alanine aminotransferase level reached 126 U per liter and thereafter plateaued at three times the upper limit of the normal . . . [Full Text of this Article]


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