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This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major clinical studies, the clinical use of this therapy, and potential adverse effects are reviewed. Relevant formal guidelines, if they exist, are presented. The article ends with the authors' clinical recommendations.
A male infant weighing 3400 g was born at 37 weeks' gestation after an uncomplicated pregnancy. The mother is a 24-year-old primipara who has type A Rh-positive blood. The infant's course in the hospital nursery was uncomplicated. Although his
The Clinical Problem
Pathophysiology and Effect of Therapy
Clinical Evidence
Clinical Use
Adverse Effects
Areas of Uncertainty
Guidelines
Recommendations
Source Information
From the Department of Pediatrics, William Beaumont Hospital, Royal Oak, MI (M.J.M.); and the Division of Gastroenterology, Department of Medicine, University of California at San Francisco, San Francisco (A.F.M.).
Address reprint requests to Dr. Maisels at William Beaumont Hospital, 3601 W. Thirteen Mile Rd., Royal Oak, MI 48073, or at jmaisels@beaumont.edu.
This article has been cited by other articles:
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