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Previous Volume 358:977 February 28, 2008 Number 9

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Edited by Victor J. Dzau and Choong-Chin Liew. 308 pp., illustrated. Malden, MA, Blackwell Futura, 2007. $144.95. ISBN 978-1-4051-3394-4.

The aim of this book is to explain modern genetics and genomics to clinical cardiologists, and it is achieved exceedingly well throughout the 12 clearly written and illustrated chapters. The first chapter provides a brief history of genetics, which quickly leads into a discussion of the Human Genome Project and gene chips. It also includes a brief but well-written primer of genes and genomics. The rest of the book's chapters are divided into three parts. Part I tackles single-gene disorders, including monogenic hypercholesterolemia, hypertrophic cardiomyopathy, dilated cardiomyopathy, other cardiomyopathies, and the long-QT syndrome. Part II takes up more complex polygenic . . . [Full Text of this Article]

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