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Volume 359:1626-1629 October 9, 2008 Number 15
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Sudden Death in Myotonic Dystrophy

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by Groh, W. J.
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To the Editor: In the study reported by Groh et al. (June 19 issue),1 during long-term follow-up of patients with myotonic dystrophy type 1, 81 of 406 patients died and one third of the deaths were sudden. How many of these deaths were really due to arrhythmia? Arrhythmia was found to be the cause of death in only 9 patients; in the other 18, data on rhythm were not available or were not decisive, and no data from autopsy are provided.

The major cause of death in the population studied is neuromuscular respiratory failure, and weakness of the respiratory muscles . . . [Full Text of this Article]



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