Edited by Ronald M. Bukowski and Andrew C. Novick. 663 pp., illustrated. Totowa, NJ, Humana Press, 2008. $149. ISBN 978-1-58829-251-3.
Renal-cell carcinoma actually comprises a heterogeneous groupof diseases with varying clinical presentations, all of whichrequire a multidisciplinary approach to treatment, with contributionsfrom urologists, pathologists, medical oncologists, radiologists,and nursing staff. The groundwork for the many advances madein renal-cell carcinoma over the past decade has its roots intwo seminal laboratory discoveries. The first was the observationin 1979 that a translocation between the short arm of chromosome3 and the long arm of chromosome 8 affected 8 of 10 membersof a family with genes linked to a hereditary form of kidneycancer. The second was . . . [Full Text of this Article]
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