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A 46-year-old woman who was not taking any medications presented with anemia and gingival hypertrophy that had been progressing over a period of 3 months. She was otherwise healthy. Histopathological evaluation of a gingival-biopsy specimen revealed a myeloblastoma. The white-cell count was 10,300 per cubic millimeter, the hematocrit was 26%, and the platelet count was 81,000 per cubic millimeter. Acute myeloid leukemia (AML) was suspected, and AML subtype M4 (according to the French–American–British classification) was finally confirmed by a repeated bone marrow biopsy 3 months later. She did not have a t(8;21) abnormality. A previous bone marrow biopsy had shown . . . [Full Text of this Article] |
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