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Previous Volume 359:1853 October 23, 2008 Number 17 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: Chemotherapy-induced nausea and vomiting is an important problem in patients with brain tumors. Because of the high prevalence of seizures, most patients are given antiepileptic drugs. Motivated by a case report,¹ we investigated whether levetiracetam can suppress chemotherapy-induced nausea and vomiting.

We retrospectively evaluated 161 patients with glioblastoma who had undergone radiation therapy and started adjuvant chemotherapy; 66 patients were taking levetiracetam and 95 were not (for all numerical data, see Table 1 in the Supplementary Appendix, available with the full text of this letter at www.nejm.org). In a univariate analysis, use of levetiracetam and older . . . [Full Text of this Article]

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