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Previous Volume 359:2018-2024 November 6, 2008 Number 19 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major clinical studies, the clinical use of this therapy, and potential adverse effects are reviewed. Relevant formal guidelines, if they exist, are presented. The article ends with the authors' clinical recommendations.

A 57-year-old man with a 60-pack-year history visits his primary care provider because he wants to quit smoking. He has a history of stable coronary artery disease, peripheral vascular disease, and hypertension. He also has severe obstructive lung disease . . . [Full Text of this Article]

The Clinical Problem

Pathophysiology and Effect of Therapy

Clinical Evidence

Clinical Use

Adverse Effects

Areas of Uncertainty

Guidelines

Recommendations

Source Information

From the Nicotine Dependence Center, Mayo Clinic College of Medicine, Rochester, MN.

Address reprint requests to Dr. Hays at the Mayo Clinic, 200 1st St. SW, Rochester, MN 55905, or at hays.taylor@mayo.edu.

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Varenicline for Tobacco Dependence
Cantrell M. A., Geraets D., Tavares A. R. Jr.
Extract | Full Text | PDF  
N Engl J Med 2009; 360:730-731, Feb 12, 2009. Correspondence

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• Rigotti, N. A. (2009). The Future of Tobacco Treatment in the Health Care System. ANN INTERN MED 150: 496-497 [Full Text]  
• Cantrell, M. A., Geraets, D., Tavares, A. R. Jr. (2009). Varenicline for Tobacco Dependence. NEJM 360: 730-731 [Full Text]  
• Schroeder, S. A. (2009). Moving Forward in Smoking Cessation: Issues for Psychiatric Nurses. J Am Psychiatr Nurses Assoc 15: 68-72