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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors' clinical recommendations.
A 29-year-old woman presents for evaluation. The previous evening, her husband, who was in the next room, heard unusual sounds and found her lying on the bed looking dazed. She was confused for a few minutes but quickly returned to normal. On questioning, she recalls an unwitnessed event about 1 month previously; at that time, she awoke feeling mildly confused, had sore
The Clinical Problem
Strategies and Evidence
Diagnosis
Evaluation
Pharmacologic Therapy
Adverse Effects
Choice of Antiepileptic Drugs in Women
Concurrent Medical Conditions
Monitoring
Areas of Uncertainty
Guidelines from Professional Societies
Conclusions and Recommendations
Source Information
From the Department of Neurology, New York University School of Medicine (J.A.F.); and the Department of Neurology, Columbia University Medical Center (T.P.) — both in New York.
An audio version of this article is available at www.nejm.org.
Address reprint requests to Dr. French at the NYU Comprehensive Epilepsy Center, 403 E. 34th St., 4th Fl., New York, NY 10016, or at jacqueline.french@nyumc.org.
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