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Previous Volume 359:166-176 July 10, 2008 Number 2 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they exist. The article ends with the authors' clinical recommendations.

A 29-year-old woman presents for evaluation. The previous evening, her husband, who was in the next room, heard unusual sounds and found her lying on the bed looking dazed. She was confused for a few minutes but quickly returned to normal. On questioning, she recalls an unwitnessed event about 1 month previously; at that time, she awoke feeling mildly confused, had sore . . . [Full Text of this Article]

The Clinical Problem

Strategies and Evidence

Diagnosis

Evaluation

Pharmacologic Therapy

            Adverse Effects

            Choice of Antiepileptic Drugs in Women

            Concurrent Medical Conditions

Monitoring

Areas of Uncertainty

Guidelines from Professional Societies

Conclusions and Recommendations

Source Information

From the Department of Neurology, New York University School of Medicine (J.A.F.); and the Department of Neurology, Columbia University Medical Center (T.P.) — both in New York.

An audio version of this article is available at www.nejm.org.

Address reprint requests to Dr. French at the NYU Comprehensive Epilepsy Center, 403 E. 34th St., 4th Fl., New York, NY 10016, or at jacqueline.french@nyumc.org.

Related Letters:

Initial Management of Epilepsy
Davis A., Pack A., Ammar H., Malani A., Mughal S., French J. A., Pedley T. A.
Extract | Full Text | PDF  
N Engl J Med 2008; 359:2499-2500, Dec 4, 2008. Correspondence

This article has been cited by other articles:

• Mancl, E. E, Gidal, B. E (2009). The Effect of Carbapenem Antibiotics on Plasma Concentrations of Valproic Acid. The Annals of Pharmacotherapy 43: 2082-2087 [Abstract] [Full Text]  
• Davis, A., Pack, A., Ammar, H., Malani, A., Mughal, S., French, J. A., Pedley, T. A. (2008). Initial Management of Epilepsy. NEJM 359: 2499-2500 [Full Text]