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Previous Volume 359:2396-2398 November 27, 2008 Number 22 Next

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To the Editor: A 41-year-old man was admitted to our hospital with ventricular tachycardia in 2003. Biopsy specimens obtained from the right ventricle showed neutral lipid deposition in cardiomyocytes. In 2004, the patient had catecholamine-dependent congestive heart failure, and a left ventricular assist system was implanted. Skeletal-muscle atrophy in the arms became evident, and staining of biopsy specimens with oil red O showed droplets of predominantly type I fibers (Figure 1A). Levels of plasma lipids and carnitine were normal.

View larger version (84K):   Figure 1. Oil Red O Staining of Biopsy Specimens from the Patient and Measures of Triglycerides and Cholesterol. Panel A shows . . . [Full Text of this Article]

 

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