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Correspondence
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Volume 359:2499-2500 December 4, 2008 Number 23
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Initial Management of Epilepsy

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 by French, J. A.
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To the Editor: With regard to the article on the initial management of epilepsy, by French and Pedley (July 10 issue),1 there are about 1 million women of reproductive age who have epilepsy in the United States. Guidelines recommend highly effective contraception, since these women have a higher pregnancy-related risk than their healthy peers.2 Contraceptive decision making for women with epilepsy can be complex because of the increased clearance of contraceptive steroids associated with some antiepileptic drugs.

The authors recommend higher-dose oral contraceptives (50 µg of ethinyl estradiol). There are multiple forms of hormonal contraception that may be affected by . . . [Full Text of this Article]




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