Wellems and Miller1 wrote of two worlds of malaria: one, ofthe residents of rural tropical areas in which the disease isendemic, and the other, of travelers to those areas, who typicallyhave greater resources. The distinction is sharp, valid, andimportant in considering the development of tools to combatthe global burden of malaria. Drugs considered safe and effectivein one world may not be so in the other.2 The majority of thehundreds of millions of people in whom malaria will developover the next year will obtain and consume antimalarial medicationwithout medical supervision. Although the . . . [Full Text of this Article]
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This article (10.1056/NEJMe0808729) was published at www.nejm.org on December 8, 2008.
From the Eijkman–Oxford Clinical Research Unit, Jakarta, Indonesia; and the Center for Tropical Medicine, Nuffield Department of Clinical Medicine, Oxford University, Oxford, United Kingdom.
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