FREE NEJM E-TOC    HOME   |   SUBSCRIBE   |   CURRENT ISSUE   |   PAST ISSUES   |   COLLECTIONS   |   Search Term  Advanced Search

Sign in | Get NEJM's E-Mail Table of Contents — Free | Subscribe

Previous Volume 359:2615-2617 December 11, 2008 Number 24 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

	Full Text PDF PDA Full Text Purchase this article Add to Personal Archive Add to Citation Manager Notify a Friend E-mail When Cited E-mail When Letters Appear Related Article by Karim, Z. PubMed Citation

To the Editor: Karim et al. (Sept. 11 issue)¹ report on three nonsynonymous nucleotide changes in NHERF1 (also called SLC9A3R1) — at p.L110V, p.R153Q, and p.E225K — which were found in 4 of 92 unrelated patients with nephrolithiasis or osteopenia. The change at p.L110V was also found in one of the controls; however, this person had reduced renal phosphate reabsorption, measured by dividing tubular maximal reabsorption of phosphate by the glomerular filtration rate (TmP/GFR), and the authors therefore suggest that this person was misclassified. The change at p.R153Q segregated with nephrolithiasis in two relatives of Patient 3, but like . . . [Full Text of this Article]

HOME  |  SUBSCRIBE  |  SEARCH  |  CURRENT ISSUE  |  PAST ISSUES  |  COLLECTIONS  |  PRIVACY  |  TERMS OF USE  |  HELP  |  beta.nejm.org Comments and questions? Please contact us. The New England Journal of Medicine is owned, published, and copyrighted © 2009 Massachusetts Medical Society. All rights reserved.