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Correspondence
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Volume 359:2617-2618 December 11, 2008 Number 24
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Successful Pregnancy after Microsurgical Transplantation of an Intact Ovary

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To the Editor: Successful human ovarian transplantation was first reported with the use of a cortical-tissue grafting technique in monozygotic twins who were discordant for premature ovarian failure.1 Subsequently, six additional cases have been reported, which have resulted in a return of ovulation in all patients, with spontaneous conception and delivery of six healthy infants, with one from tissue that had been frozen.2 The concept of ovarian cortical grafting is based on the fact that all follicles containing eggs are located in the outer 1 mm of the ovary, which can be sutured to the recipient's medulla just like a . . . [Full Text of this Article]


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