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Volume 359:482-491 July 31, 2008 Number 5
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Smoke-free Legislation and Hospitalizations for Acute Coronary Syndrome
Jill P. Pell, M.D., Sally Haw, B.Sc., Stuart Cobbe, M.D., David E. Newby, Ph.D., Alastair C.H. Pell, M.D., Colin Fischbacher, M.B., Ch.B., Alex McConnachie, Ph.D., Stuart Pringle, M.D., David Murdoch, M.B., Ch.B., Frank Dunn, M.D., Keith Oldroyd, M.D., Paul MacIntyre, M.D., Brian O'Rourke, M.D., and William Borland, B.Sc.

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ABSTRACT

Background Previous studies have suggested a reduction in the total number of hospital admissions for acute coronary syndrome after the enactment of legislation banning smoking in public places. However, it is unknown whether the reduction in admissions involved nonsmokers, smokers, or both.

Methods Since the end of March 2006, smoking has been prohibited by law in all enclosed public places throughout Scotland. We collected information prospectively on smoking status and exposure to secondhand smoke based on questionnaires and biochemical findings from all patients admitted with acute coronary syndrome to nine Scottish hospitals during the 10-month period preceding the passage of the legislation and during the same period the next year. These hospitals accounted for 64% of admissions for acute coronary syndrome in Scotland, which has a population of 5.1 million.

Results Overall, the number of admissions for acute coronary syndrome decreased from 3235 to 2684 — a 17% reduction (95% confidence interval, 16 to 18) — as compared with a 4% reduction in England (which has no such legislation) during the same period and a mean annual decrease of 3% (maximum decrease, 9%) in Scotland during the decade preceding the study. The reduction in the number of admissions was not due to an increase in the number of deaths of patients with acute coronary syndrome who were not admitted to the hospital; this latter number decreased by 6%. There was a 14% reduction in the number of admissions for acute coronary syndrome among smokers, a 19% reduction among former smokers, and a 21% reduction among persons who had never smoked. Persons who had never smoked reported a decrease in the weekly duration of exposure to secondhand smoke (P<0.001 by the chi-square test for trend) that was confirmed by a decrease in their geometric mean concentration of serum cotinine from 0.68 to 0.56 ng per milliliter (P<0.001 by the t-test).

Conclusions The number of admissions for acute coronary syndrome decreased after the implementation of smoke-free legislation. A total of 67% of the decrease involved nonsmokers. However, fewer admissions among smokers also contributed to the overall reduction.


Source Information

From the University of Glasgow (J.P.P., S.C., A.M.), Southern General Hospital (D.M.), Stobhill Hospital (F.D.), Western Infirmary (K.O.), and Western General Hospital (W.B.) — all in Glasgow; University of Edinburgh (S.H., D.E.N.) and Information Services Division (C.F.) — both in Edinburgh; Monklands Hospital, Airdrie (A.C.H.P.); Ninewells Hospital, Dundee (S.P.); Royal Alexandra Hospital, Paisley (P.M.); and Hairmyers Hospital, East Kilbride (B.O.) — all in the United Kingdom.

Address reprint requests to Dr. J. Pell at Rm. 305, Public Health Section, University of Glasgow, 1 Lilybank Gardens, Glasgow G12 8RZ, United Kingdom, or at j.pell{at}clinmed.gla.ac.uk.

Full Text of this Article


Related Letters:

Smoke-free Legislation and Acute Coronary Syndrome
Eisner M. D.
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N Engl J Med 2008; 359:2070, Nov 6, 2008. Correspondence

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N Engl J Med 2008; 359:2070-2071, Nov 6, 2008. Correspondence

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