Smoke-free Legislation and Hospitalizations for Acute Coronary Syndrome
Jill P. Pell, M.D., Sally Haw, B.Sc., Stuart Cobbe, M.D., David E. Newby, Ph.D., Alastair C.H. Pell, M.D., Colin Fischbacher, M.B., Ch.B., Alex McConnachie, Ph.D., Stuart Pringle, M.D., David Murdoch, M.B., Ch.B., Frank Dunn, M.D., Keith Oldroyd, M.D., Paul MacIntyre, M.D., Brian O'Rourke, M.D., and William Borland, B.Sc.
Background Previous studies have suggested a reduction in thetotal number of hospital admissions for acute coronary syndromeafter the enactment of legislation banning smoking in publicplaces. However, it is unknown whether the reduction in admissionsinvolved nonsmokers, smokers, or both.
Methods Since the end of March 2006, smoking has been prohibitedby law in all enclosed public places throughout Scotland. Wecollected information prospectively on smoking status and exposureto secondhand smoke based on questionnaires and biochemicalfindings from all patients admitted with acute coronary syndrometo nine Scottish hospitals during the 10-month period precedingthe passage of the legislation and during the same period thenext year. These hospitals accounted for 64% of admissions foracute coronary syndrome in Scotland, which has a populationof 5.1 million.
Results Overall, the number of admissions for acute coronarysyndrome decreased from 3235 to 2684 — a 17% reduction(95% confidence interval, 16 to 18) — as compared witha 4% reduction in England (which has no such legislation) duringthe same period and a mean annual decrease of 3% (maximum decrease,9%) in Scotland during the decade preceding the study. The reductionin the number of admissions was not due to an increase in thenumber of deaths of patients with acute coronary syndrome whowere not admitted to the hospital; this latter number decreasedby 6%. There was a 14% reduction in the number of admissionsfor acute coronary syndrome among smokers, a 19% reduction amongformer smokers, and a 21% reduction among persons who had neversmoked. Persons who had never smoked reported a decrease inthe weekly duration of exposure to secondhand smoke (P<0.001by the chi-square test for trend) that was confirmed by a decreasein their geometric mean concentration of serum cotinine from0.68 to 0.56 ng per milliliter (P<0.001 by the t-test).
Conclusions The number of admissions for acute coronary syndromedecreased after the implementation of smoke-free legislation.A total of 67% of the decrease involved nonsmokers. However,fewer admissions among smokers also contributed to the overallreduction.
Source Information
From the University of Glasgow (J.P.P., S.C., A.M.), Southern General Hospital (D.M.), Stobhill Hospital (F.D.), Western Infirmary (K.O.), and Western General Hospital (W.B.) — all in Glasgow; University of Edinburgh (S.H., D.E.N.) and Information Services Division (C.F.) — both in Edinburgh; Monklands Hospital, Airdrie (A.C.H.P.); Ninewells Hospital, Dundee (S.P.); Royal Alexandra Hospital, Paisley (P.M.); and Hairmyers Hospital, East Kilbride (B.O.) — all in the United Kingdom.
Address reprint requests to Dr. J. Pell at Rm. 305, Public Health Section, University of Glasgow, 1 Lilybank Gardens, Glasgow G12 8RZ, United Kingdom, or at j.pell{at}clinmed.gla.ac.uk.
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