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Editorial
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Volume 359:518-520 July 31, 2008 Number 5
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Time to Take Myocardial Reperfusion Injury Seriously
Derek J. Hausenloy, M.D., Ph.D., and Derek M. Yellon, Ph.D., D.Sc.

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 by Piot, C.
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Every year, 500,000 people in the United States have an ST-elevation myocardial infarction.1 Timely and effective reperfusion with the use of either primary percutaneous coronary intervention (PCI) or thrombolytic therapy remains the most effective treatment strategy for limiting the size of the myocardial infarct, preserving left ventricular ejection fraction, and improving the clinical outcomes in such patients. However, despite optimal reperfusion therapy, morbidity and mortality remain substantial, with about 5 to 6% of patients having a subsequent cardiovascular event by 30 days.2

One treatment strategy that might reduce the size of the infarct and improve the clinical outcomes in these . . . [Full Text of this Article]


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From the Hatter Cardiovascular Institute and Centre for Cardiology, University College London Hospitals and Medical Schools, London.




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