Twenty-five years ago, care for patients with symptomatic coronaryartery disease centered on the selection and titration of antianginalmedications. Percutaneous coronary intervention (PCI), whichwas limited at that time to balloon angioplasty, was an alternative.However, the risks associated with the procedure and the rateof restenosis largely relegated it to second-line therapy forpatients who did not have a response to best medical therapy.Fast-forward to the present. Coronary stents have revolutionizedPCI and have reduced the rate of complications and the needfor repeat interventions. This advance has markedly alteredclinicians' thresholds for considering PCI. Now, the . . . [Full Text of this Article]
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From the Duke Clinical Research Institute, Duke University Medical Center, Durham, NC (E.D.P.); and the Denver Veterans Affairs Medical Center and University of Colorado Denver Health Sciences Center, Denver (J.S.R.).
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Quality of Life with PCI versus Medical Therapy in Stable Coronary Disease
Beltrame J. F., Tavella R., Cutri N., Rodriguez A. E., Maree A. O., Palacios I. F., Reppel M., Radke P. W., Schunkert H., Kinlay S., Brown R. A., Teirstein P. S., Kandzari D. E., Smith J., Weintraub W. S., Kolm P., Boden W. E., Peterson E. D., Rumsfeld J. S.
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N Engl J Med 2008;
359:2289-2293, Nov 20, 2008.
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