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Previous Volume 359:977-979 August 28, 2008 Number 9 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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To the Editor: We report on a patient with type 1 diabetes mellitus, diagnosed at 16 years of age, in whom widespread amyloid deposits developed many years later in transplanted human islets. The islets were administered through three intraportal infusions: two infusions were administered 4 months apart when the patient was 50 years of age, and one infusion was administered when he was 54 years of age.

Before the first implantation, the treatment of the patient, who had a functioning renal transplant, was switched to the Edmonton immunosuppression protocol (i.e., daclizumab, tacrolimus, and sirolimus). After the second islet transplantation, the . . . [Full Text of this Article]

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Amyloid and Transplanted Islets
Rickels M. R., Collins H. W., Naji A., Westermark G. T., Korsgren O., Westermark P.
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N Engl J Med 2008; 359:2729-2731, Dec 18, 2008. Correspondence

This article has been cited by other articles:

• Kaddis, J. S., Olack, B. J., Sowinski, J., Cravens, J., Contreras, J. L., Niland, J. C. (2009). Human Pancreatic Islets and Diabetes Research. JAMA 301: 1580-1587 [Abstract] [Full Text]  
• Rickels, M. R., Collins, H. W., Naji, A., Westermark, G. T., Korsgren, O., Westermark, P. (2008). Amyloid and Transplanted Islets. NEJM 359: 2729-2731 [Full Text]