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A healthy 84-year-old woman presented with a 6-month history of a slowly growing asymptomatic lesion on the dorsum of her right hand. Physical examination revealed a keratotic cutaneous horn — approximately 6 to 7 cm in length and yellow-gray in color, with a firm consistency — on the dorsoulnar aspect of the base of the right index finger (also involving the web between the index and middle fingers), without associated lymphadenopathy. The lesion was completely excised surgically. Histologic examination showed neoplastic proliferation of atypical keratinocytes extending into the dermis, with large hyperchromatic and pleomorphic nuclei. On the basis of the . . . [Full Text of this Article] |
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