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Previous Volume 360:78-80 January 1, 2009 Number 1 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Organ transplantation is one of the great success stories of modern medicine. Living-donor kidney transplantations between identical twins during the early 1950s first demonstrated the overall feasibility of this procedure and ultimately paved the way to long-term success. Outcomes improved rapidly with a greater understanding of the immunobiology of graft rejection, with more refined surgical techniques, with scientific advancements in fields related to transplantation, and, most importantly, with the advent and continuous refinement of immunosuppressive agents.

Research in the area of organ procurement and preservation began even before the first successful clinical transplantations. Before World War II, in France Alex . . . [Full Text of this Article]

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From the Division of Transplant Surgery (S.G.T.) and the Department of Pathology (G.G.-C.), Brigham and Women's Hospital, and Harvard Medical School, Boston.

Related Letters:

Machine Perfusion or Cold Storage in Deceased-Donor Kidney Transplantation
Ray C., Sohrabi S., Talbot D., Knox Cartwright N., Moers C., Maathuis M.-H. J., Ploeg R. J., Tullius S. G., García-Cardeña G.
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N Engl J Med 2009; 360:1460-1461, Apr 2, 2009. Correspondence

This article has been cited by other articles:

• Ray, C., Sohrabi, S., Talbot, D., Knox Cartwright, N., Moers, C., Maathuis, M.-H. J., Ploeg, R. J., Tullius, S. G., Garcia-Cardena, G. (2009). Machine perfusion or cold storage in deceased-donor kidney transplantation.. NEJM 360: 1460-1461 [Full Text]