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Correspondence
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Volume 360:87-88 January 1, 2009 Number 1
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Lung Cancer

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 by Herbst, R. S.
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To the Editor: In the introductory remarks of their article, Herbst et al. (Sept. 25 issue)1 note, "Smoking causes all types of lung cancer but is most strongly linked with small-cell lung cancer and squamous-cell carcinoma." In the legend to Figure 1, they also note, "Most tumors that are not related to smoking are adenocarcinomas and develop in the peripheral airways." This statement almost echoes Kreyberg's observation2 in 1962 regarding the "slight, if any" relationship between cigarette smoking and adenocarcinoma of the lung.

In the past 47 years, adenocarcinoma has become the predominant type of cancer cell in male smokers . . . [Full Text of this Article]




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