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A 42-year-old woman was admitted with hypotension. Sepsis was diagnosed, which was probably caused by cellulitis related to chronic severe edema, skin breakdown, and lichenification of both legs (Panels A and B). Blood cultures were negative. The patient had a history of lymphedema tarda in the legs and had been admitted several times before with recurrent cellulitis. Her mother and sister both had the same condition. Lymphedema is characterized by a regional accumulation of excessive amounts of interstitial protein-rich fluid. Lymphedema tarda is a congenital disease, although the clinical manifestations may not become evident for several decades. The disease was . . . [Full Text of this Article] |