Seemingly from one influenza season to the next, we have lostthe use of our leading antiviral influenza drug because of resistance.This winter, the circulating strain of seasonal influenza Avirus (H1N1) is resistant to the neuraminidase inhibitor oseltamivir.Moreover, rather than emerging under selective pressure of druguse, as many antibiotic-resistant bacteria do and as has beenthe concern for influenza, this resistant strain seems to bea natural, spontaneously arising variant. Nevertheless, sciencehas given us the tools with which to anticipate these events— and should allow us to develop new clinical solutionsthat build on . . . [Full Text of this Article]
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Dr. Moscona is a professor in the Departments of Pediatrics and Microbiology and Immunology at Weill Medical College of Cornell University, New York.
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