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Previous Volume 360:1144-1146 March 12, 2009 Number 11 Next

	Since this article has no abstract, we have provided an extract of the first 100 words of the full text and any section headings.

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Atherosclerosis is reversible and involves the removal of trapped cholesterol-loaded foam-cell macrophages from the arterial intima. A recent study by Park and colleagues¹ showed that these foam cells are trapped by interaction with oxidized low-density lipoprotein (LDL) and can be remobilized by dynamic exposure to key antioxidants such as resveratrol, a polyphenolic compound found in grapes and red wine and having potential antiatherogenic properties.²

It was once thought that atherosclerosis was a lipid-storage disease and that its pathology — a lesion or plaque causing arterial obstruction — resulted from the accumulation of lipid within arteries. It is now understood that . . . [Full Text of this Article]

Source Information

From the Department of Immunology and Microbial Sciences, Scripps Research Institute, La Jolla, CA.

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