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A 52-year-old woman from southern Tunisia presented with a 2-year history of an asymptomatic, thick, reddish plaque on her right ear. The lesion began as multiple erythematous papules that later coalesced to form an infiltrated plaque covering a large part of the auricle (Panel A). Histopathological examination (hematoxylin and eosin stain) revealed epithelioid granulomas suggestive of leishmaniasis, tuberculosis, or sarcoidosis (Panel B). Leishmania amastigotes were not found in smears taken from the lesion, and cultures were negative. A smear and culture for acid-fast bacilli were also negative. A polymerase-chain-reaction (PCR) assay performed on a second biopsy specimen was positive for . . . [Full Text of this Article] |