To the Editor: Cecil and colleagues (Dec. 11 issue)1 reportthat the A allele of the fat mass and obesity–associated(FTO) gene variant rs9939609, which has been associated withobesity, is also associated with increased levels of physicalactivity in children. No differences in resting energy expenditurewere observed. The association between the A allele and body-massindex (BMI) was explained by a relative overconsumption of food.
The Malmö Preventive Project is a population-based studyof adults from Malmö, Sweden, in which anthropometry wasperformed and self-reported physical activity was assessed.2We genotyped the rs9939609 variant in 15,931 . . . [Full Text of this Article]
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